Covid-19

[Muskie in dayton]

Follow the science or Listen to science has to be one of the most overrated sayings of all time. Science has become politicalized just like everything else we do as a nation and its amazing people still listen to the media.

The science is only politicized by politicians/politically biased news outlets (which are most). That’s why it’s important to get info right from science and medical sources. I realize that’s a big ask for most people. But if that happened or if the news fairly reported the facts, we wouldn’t be doing the stupid things we’re doing which are far more detrimental than the virus.

[X-man]

Big jump in Ohio covid cases today, the most since April 21 other than May 8. Hopefully this is a blip and not a trend.

[xu82]

Big jump in Ohio covid cases today, the most since April 21 other than May 8. Hopefully this is a blip and not a trend.

Georgia swings WILDLY from day to day, so I try to watch the 7 day moving average to see the big picture, which still looks fairly positive (as far as I can tell). Hope the overall trend in Ohio is also positive news.

https://dph.georgia.gov/covid-19-daily-status-report

[kmcrawfo]

I found this one interesting:

https://dgalerts.docguide.com/eviden...erID=106676631

Helps explain why very young children may be less contagious. Also, oral-fecal spread looking to be more likely over time. We are learning about this bug....

[Muskie in dayton]

I found this one interesting:

https://dgalerts.docguide.com/eviden...erID=106676631

Helps explain why very young children may be less contagious. Also, oral-fecal spread looking to be more likely over time. We are learning about this bug....

Interesting. Is it possible medically or pharmaceutically to reduce the expression of ACE2 as people age, as a possible treatment?

Also to the oral-fecal spread, I’m not into that but someone better get word to the porn industry! :-)

[paulxu]

This seems to be one of the first large scale tests of the drug therapies, alone and in combination. Results not very promising:

https://www.cnn.com/us/live-news/us-...0c916b21bc0959

[boozehound]

This seems to be one of the first large scale tests of the drug therapies, alone and in combination. Results not very promising:

https://www.cnn.com/us/live-news/us-...0c916b21bc0959

I wouldn't call it particularly surprising, at least to me. I wasn't really expecting us dusting off an old treatment for another illness to be a game-changer for COVID. It would have been extremely fortuitous had it been the case, particularly given the fact that treatments for viruses never seem to be a total cure (example: Tamiflu).

There's still a good bit of promising news, particularly on the vaccination front, so that's encouraging. Hopefully we can find a way to improve treatments as we learn more about the disease.

[Lloyd Braun]

Interesting. Is it possible medically or pharmaceutically to reduce the expression of ACE2 as people age, as a possible treatment?

Also to the oral-fecal spread, I’m not into that but someone better get word to the porn industry! :-)

Gene expression is fairly difficult to prevent. A treatment that has had good results however is somewhat counterintuitive: Using ACE 2. When injected, recombinant ACE 2 has been shown to improve lung recovery among other things. This is a good study to summarize that although wordy and fairly scientific. If interested I could formulate a cliffs notes version (do they still make cliffs notes?) this weekend with free time.

[paulxu]

How does the plasma deal work?
Somebody gets it but it doesn't hurt them, and they develop antibodies.
Then you take some of their blood, extract plasma...and give it to someone who is sufffereing...or anybody, like a vaccine?

[Lloyd Braun]

How does the plasma deal work?
Somebody gets it but it doesn't hurt them, and they develop antibodies.
Then you take some of their blood, extract plasma...and give it to someone who is sufffereing...or anybody, like a vaccine?

Pretty much the antibodies taken from the individual whom has produced their own are transferred into someone currently fighting off the virus. This is called passive immunity. An easy comparison is when a mother breast feeds an infant which passes circulating antibodies through milk (or in utero through circulation). Convalescent plasma has not had great results yet, mostly because they are administering it to the sickest of individuals. There is also question to how many antibodies (concentration) those that have donated even have. This disease is not old and the immune response is still unknown.