Covid-19

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Originally Posted by Xville

Nice pee wee Herman reply

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Ok Ville, here's what I completely understand.
- The vax is helpful and people should get it but it's none of your or the Gov't's GD business
- The masks and lockdowns did not have the intended effect last year. In fact, they led to greater societal problems with mental health, substance abuse, divorce and a devastated economy
- Masks do not significantly slow the transmission of the virus
- Anecdotal stories are not evidence of anything meaningful in this conversation or others
- 70% of the population has been vaccinated and more have antibodies which is pretty good for a couple of months into this
- The vaccinated can still get, spread and cause mutations of the virus
- It may be time to start building and staffing separate treatment centers for COVID much like was done with TB
- Finally, people need to accept the fact that this isn't going away, do what they, and they alone can do to for themselves

What I don't know much about are the treatments available. I'd like to know more about that as it will become more important than short sighted band aid measures like masks and social media posts.

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Originally Posted by Strange Brew

Thanks to you both. Could you indulge me with a high level PSA on the various treatments? Frankly, lot is out there in the wind and I don’t know what everything actually does.

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Give me a couple days and I can type up a google drive document with background, some of the clinical research done of each particular treatment, indications, the mechanism of action, side effects, and it's place in treatment right now, I don't want to type all of that into the board and have a post the size of an essay, I rather be completely comprehensive and not cut corners, plus it'd be beneficial for a lot of people and easily sharable that way I think.

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Originally Posted by GIMMFD

Give me a couple days and I can type up a google drive document with background, some of the clinical research done of each particular treatment, indications, the mechanism of action, side effects, and it's place in treatment right now, I don't want to type all of that into the board and have a post the size of an essay, I rather be completely comprehensive and not cut corners, plus it'd be beneficial for a lot of people and easily sharable that way I think.

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Hi, no need to go to that much trouble unless you want to. But I’ll gladly take any info as that will likely become increasingly important (my opinion).

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Originally Posted by Strange Brew

Hi, no need to go to that much trouble unless you want to. But I’ll gladly take any info as that will likely become increasingly important (my opinion).

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Honestly have had a lot of requests (phone calls, texts, etc.) about the topic and genuine questions I think it'll be beneficial to a broad spectrum of people, so I really don't mind, will save me time in the long run haha. I just wanna make sure I have the latest research and guidelines before I make some wild erroneous claim, I rather have just a scientific presentation of it, and be unbiased backed by the studies.

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Originally Posted by GIMMFD

Honestly have had a lot of requests (phone calls, texts, etc.) about the topic and genuine questions I think it'll be beneficial to a broad spectrum of people, so I really don't mind, will save me time in the long run haha. I just wanna make sure I have the latest research and guidelines before I make some wild erroneous claim, I rather have just a scientific presentation of it, and be unbiased backed by the studies.

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Thank you! Good to know there’s plenty of work in motion on treatments.

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Originally Posted by Strange Brew

Thank you! Good to know there’s plenty of work in motion on treatments.

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Disclaimer: I am coming off a long week of long shifts, and am jaded by people without vaccination or prior immunity repeatedly seeking last minute treatment when it is later in the course of illness because they are scared and can’t breathe.

The best treatment is prevention. The best outpatient treatment for infection we have is the mAb treatment with 60-70% risk reduction in complication, which may wane with further variants. Compared to less than 0.1% at worst hospitalization rate in vaccinated folks there is no comparison. There are even studies showing that when it is given to asymptomatic household members early it is extraordinarily successful.

However when breakthrough infections occur in immunocompromised individuals the available treatments are variably effective as perhaps GIMMFD will show. Nip it in the bud…

But talking about treatments at this point is kind of funny. Because we have a vaccine

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Originally Posted by Lloyd Braun

Disclaimer: I am coming off a long week of long shifts, and am jaded by people without vaccination or prior immunity repeatedly seeking last minute treatment when it is later in the course of illness because they are scared and can’t breathe.

The best treatment is prevention. The best outpatient treatment for infection we have is the mAb treatment with 60-70% risk reduction in complication, which may wane with further variants. Compared to less than 0.1% at worst hospitalization rate in vaccinated folks there is no comparison. There are even studies showing that when it is given to asymptomatic household members early it is extraordinarily successful.

However when breakthrough infections occur in immunocompromised individuals the available treatments are variably effective as perhaps GIMMFD will show. Nip it in the bud…

But talking about treatments at this point is kind of funny. Because we have a vaccine

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Understand. Not easy helping those that won’t help themselves..

Hoping the treatments are effective as the virus develops/mutates.

Yea exactly, that’s the million dollar question with any covid treatment… will it last? I have seen slightly less efficacy with this variant. Which is what makes full FDA approval kind of moot with vaccines or treatment IMO.

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Originally Posted by Strange Brew

Ok Ville, here's what I completely understand.
- The vax is helpful and people should get it but it's none of your or the Gov't's GD business
- The masks and lockdowns did not have the intended effect last year. In fact, they led to greater societal problems with mental health, substance abuse, divorce and a devastated economy
- Masks do not significantly slow the transmission of the virus
- Anecdotal stories are not evidence of anything meaningful in this conversation or others
- 70% of the population has been vaccinated and more have antibodies which is pretty good for a couple of months into this
- The vaccinated can still get, spread and cause mutations of the virus
- It may be time to start building and staffing separate treatment centers for COVID much like was done with TB
- Finally, people need to accept the fact that this isn't going away, do what they, and they alone can do to for themselves

What I don't know much about are the treatments available. I'd like to know more about that as it will become more important than short sighted band aid measures like masks and social media posts.

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So you didn’t understand…glad we got that sorted out. It’s not just covid itself that’s the issue. Anyways, It is my business because there are ramifications of covid that could greatly affect my business and the small/medium sized businesses I partner with, and it ia certainly the government’s business since part of their job is to protect its citizens even if some of them are completely clueless.

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Originally Posted by Xville

So you didn’t understand…glad we got that sorted out. It’s not just covid itself that’s the issue. Anyways, It is my business because there are ramifications of covid that could greatly affect my business and the small/medium sized businesses I partner with, and it ia certainly the government’s business since part of their job is to protect its citizens even if some of them are completely clueless.

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No. It’s not the Gov’ts business. Period Ville.

Edit: ask the Americans in Kabul about the Gov’t’s role in protecting them…